D(+) Mannose 99 % For Biochemistry 25 gr

SKU : O-5299.0025
CAS : 3458-28-4
Formula : C6H12O6
Grade : for biochemistry
Primary Applications in Biochemistry :
  • Glycosylation Studies: Used to investigate the synthesis of N-linked glycoproteins, cell surface receptors, and structural glycans in eukaryotic cell systems.
  • Microbiological Media: Serves as a specific carbon source in bacterial fermentation studies, particularly to evaluate the growth differentiation and transport mechanisms of enteric bacteria.
  • Bacterial Adherence Inhibition: Utilized in anti-adhesion assays to study how D-mannose competitively binds to FimH adhesins on Type 1 fimbriae of Escherichia coli, preventing the bacteria from attaching to host cell walls.
  • Enzyme Assays: Acts as a substrate for studying the kinetics and structural mechanics of enzymes like hexokinase, phosphomannose isomerase, and mannosidases

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Mannose is a sugar with the formula HOCH2(CHOH)4CHO, which sometimes is abbreviated Man. It is one of the monomers of the aldohexose series of carbohydrates. It is a C-2 epimer of glucose. Mannose is important in human metabolism, especially in the glycosylation of certain proteins. Several congenital disorders of glycosylation are associated with mutations in enzymes involved in mannose metabolism.D(+) Mannose 99% For Biochemistry is an ultra-pure, naturally occurring aldohexose sugar primarily used as a vital carbon source, cellular substrate, and reference standard in biochemical, microbiological, and glycobiology research. The “For Biochemistry” designation ensures the carbohydrate is free from interfering trace sugars, heavy metals, and enzymatic inhibitors that could compromise metabolic or cellular assays. 
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